COMPARATIVE GENOMIC ANALYSIS OF LACTICASEIBACILLUS PARACASEI SMN-LBK FROM KOUMISS

Comparative genomic analysis of Lacticaseibacillus paracasei SMN-LBK from koumiss

Comparative genomic analysis of Lacticaseibacillus paracasei SMN-LBK from koumiss

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Lacticaseibacillus paracasei SMN-LBK, which was isolated in Xinjiang, has been shown to be a probiotic strain and used as the auxiliary starter for dairy fermentation.Comparative genomic analysis was performed to investigate the metabolic preference and ethanol tolerance mechanisms of L.paracasei SMN-LBK.

The results of comparative genomics showed that L.paracasei strains had high conservation and genetic diversity.SMN-LBK encoded Keepsakes various genes related to carbohydrate and amino acid metabolism pathways, which endow this strain with good fermentation potential.

In addition, 6 CRISPR sequences and 8 cas proteins were found in SMN-LBK, and these could play vital roles in the immune system.Furthermore, a unique cluster of potential secondary metabolism genes related to bacteriocins was detected in the genome of SMN-LBK, and this could be important for the Pre-Rolls preservation of fermented foods.Multiple genes related to alcohol tolerance were also identified.

In conclusion, our study explained the traits that were previously demonstrated for SMN-LBK as phenotypes and provided a theoretical basis for the application of SMN-LBK in the food industry.

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